Advanced Diploma in Organic Chemistry in Biology and Drug Development
Course Description
Organic Chemistry in Biology and Drug Development starts with a concise discussion of the different biochemical processes where organic chemistry plays a dominant role. Next, you will study the general concepts of drug design principles. This will be followed by different kinds of drugs and the chemistry of neurotransmitters. After this, you will learn about high throughput screening and combinatorial chemistry.
You will then study the design strategy of antiviral drugs, antimicrobial compounds and the polyketides in connection with the erythromycin polyketides biosynthesis. You will also learn about antiulcer agents which can either be H₂ (hydrogen) antagonists or proton pump inhibitors and antihypertensive drugs. Lastly, you will study the pharmacokinetics and pharmacodynamics of the drug discovery process. This will be followed by the quantitative structure-activity relationship (QSAR), which include principles that can be used to quantify the biological activity of a drug.
This diploma course will be of great interest to professionals working in the pharmaceutical industry such as chemists, biochemists, chemical biologists, druggists and pharmacists. It will equally benefit any learner who would like to have a career in the pharmaceutical sector. So, check out the course and kickstart an exciting career in the field of organic chemistry and drug development.
What you'll learn in this course?
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Virus
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Molecular Biology
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Cancer
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Drugs
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Pharmaceuticals (Pharma)
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Organic Chemistry
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Biology
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Chemistry
Course Curriculum
- Learning Outcomes
- A Brief Introduction to Molecules of Life: Structure of Amino Acids and their Various Charge Form
- Biological Macromolecules and Small Molecules: Importance and Functions
- Amino Acids: The Building Block of Proteins
- Amino Acids: Separation and Detection, Electrophoresis, and Ninhydrin Reaction
- Lesson Summary
- Learning Outcomes
- Method of Determination of Amino Acid Sequence: Primary Structure of Polypeptides/Proteins
- Selective Peptide Bond Cleavage: Enzymatic and Non-enzymatic Methods
- Peptide Synthesis: Protecting Groups for Amine and Carboxyl Functionality
- Peptide Synthesis: Protection, Coupling and Deprotection Methods
- Recent Development of Coupling Agents: Merrifield’s Method Solid Phase Peptide Synthesis
- Lesson Summary
- Learning Outcomes
- Hierarchical Structure of Proteins: Secondary, Tertiary and Quaternary Structure
- Ramachandran Plot and Protein Purification Techniques
- Protein Purification Techniques
- Introduction to Enzymes and its Kinetics
- Enzyme Catalyzed Reactions and Introduction to the Catalytic Activity of Proteases
- Lesson Summary
- Learning Outcomes
- Introduction to the Drug Discovery Process
- Fundamental Principles of Drug Development Process
- Combinatorial Chemistry
- Neurotransmitters
- Catechol Amine Based and GABA Neurotransmitters
- Hypertension: Humoral Mechanism and Renin/Angiotensin System
- Inhibitor Design of Angiotensin Converting Enzyme.
- Lesson Summary
NPTEL
India
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