Diploma in Molecules of Life and Enzymes
Course Description
Organic Chemistry in Biology - An Introduction to Molecules of Life and Enzymes starts with a concise discussion of some of the different biochemical processes where organic chemistry plays a dominant role. Next, you will study the biological macromolecules and small molecules, amino acids, methods of determining an amino acid sequence, peptide synthesis, and selective peptide bond cleavage.
You will then be introduced to the Ramachandran plot, protein purification techniques, recent development of coupling agents, hierarchical structure of proteins, enzymes and its kinetics, enzymes catalysed reactions, and catalytic activity of proteases. You will also learn about the concept of enzyme kinetics, and enzyme inhibition.
This certificate course in an introduction to the molecules of life and enzymes will be of great interest to professionals starting to work in the pharmaceutical industry such as chemists, biochemists, chemical biologists and pharmacists. It will equally benefit any learner who would like to have a career in the pharmaceutical sector or field of organic chemistry.
What you'll learn in this course?
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Molecular Biology
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Science
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Organic Chemistry
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Biochemistry
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Biology
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Chemistry
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Pharmacology
Course Curriculum
- Learning Outcomes
- Structure of Amino Acids and their Various Charge Form
- Biological Macromolecules and Small Molecules: Importance and Functions
- Amino Acids: The Building Block of Proteins
- Amino Acids: Separation and Detection, Electrophoresis, and Ninhydrin Reaction
- Method of Determination of Amino Acid Sequence: Primary Structure of Polypeptides/Proteins
- Selective Peptide Bond Cleavage: Enzymatic and Non-enzymatic Methods
- Peptide Synthesis: Protecting Groups for Amine and Carboxyl Functionality
- Peptide Synthesis: Protection, Coupling and Deprotection Methods
- Recent Development of Coupling Agents: Merrifield’s Method Solid Phase Peptide Synthesis
- Lesson Summary
- Learning Outcomes
- Hierarchical Structure of Proteins: Secondary, Tertiary and Quaternary Structure
- Ramachandran Plot and Protein Purification Techniques
- Protein Purification Techniques
- Introduction to Enzymes and its Kinetics
- Enzyme Catalyzed Reactions and Introduction to the Catalytic Activity of Proteases
- Enzymes Kinetics
- Concept of Enzyme Inhibition
- Irreversible Inhibition
- Problems on Enzyme Kinetics and Enzyme Inhibition.
- Lesson Summary
NPTEL
India
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